An elastohydrodynamic lubrication model for a rigid ball in contact with a transversely isotropic half-space is constructed. Reynolds equation, film thickness equation, and load balance equation are solved using the finite difference method, where the surface vertical displacement or deformation of transversely isotropic half-space is considered through the film thickness equation. The numerical methods are verified by comparing the displacements and stresses with those from Hertzian analytical solutions. Furthermore, the effects of elastic moduli, entertainment velocities, and lubricants on fluid pressure, film thickness, and von Mises stress are analyzed and discussed under a constant load. Finally, the modified Hamrock–Dowson equations for transversely isotropic materials to calculate central film thickness and minimum film thickness are proposed and validated.